Cmax and AUC are the two key pharmacokinetic measures used to prove generic drugs work like brand-name versions. Cmax shows peak concentration, AUC shows total exposure-both must fall within 80%-125% for approval.
Doctors prescribe generics for 90% of medications, but many lack training on bioequivalence. Learn why knowledge gaps persist, how real-world feedback changes prescribing, and what's being done to fix it.
Authorized generics are identical to brand-name drugs but sold under a different label. As of 2026, only a handful are available due to FTC crackdowns and market shifts. Learn which ones are still on the market and how to identify them.
Modified-release formulations require special bioequivalence testing to ensure generics work as safely and effectively as brand-name drugs. Learn the key regulatory requirements, common pitfalls, and why standard tests aren't enough.